Search results for "Marine compounds"

showing 2 items of 2 documents

Biochemical characterization of cassiopea andromeda (Forsskål, 1775), another red sea jellyfish in the western mediterranean sea

2021

Increasing frequency of native jellyfish proliferations and massive appearance of non-indigenous jellyfish species recently concur to impact Mediterranean coastal ecosystems and human activities at sea. Nonetheless, jellyfish biomass may represent an exploitable novel resource to coastal communities, with reference to its potential use in the pharmaceutical, nutritional, and nutraceutical Blue Growth sectors. The zooxanthellate jellyfish Cassiopea andromeda, Forsskål, 1775 (Cnidaria, Rhizostomeae) entered the Levant Sea through the Suez Canal and spread towards the Western Mediterranean to reach Malta, Tunisia, and recently also the Italian coasts. Here we report on the biochemical characte…

0106 biological sciencesMediterranean climateCnidariacollagenAquatic OrganismsJellyfishScyphozoaPharmaceutical Scienceantioxidant activityalien species01 natural sciencesBioactive marine compoundMediterranean seaDrug DiscoverySuez canalAlien species; Antioxidant activity; Antioxidants; Bioactive marine compounds; Collagen; Fatty acids; Jellyfish; Nutraceuticals; Zooxanthellate jellyfish; Animals; Antioxidants; Aquatic Organisms; Ecosystem; Mediterranean Sea; Dietary Supplements; ScyphozoaBiology (General)Pharmacology Toxicology and Pharmaceutics (miscellaneous)nutraceuticals0303 health sciencesAquatic Organismjellyfishzooxanthellate jellyfishAlien species Antioxidant activity Antioxidants Bioactive marine compounds Collagen Fatty acids Jellyfish Nutraceuticals Zooxanthellate jellyfish Animals Antioxidants Aquatic Organisms Ecosystem Mediterranean Sea Dietary Supplements ScyphozoaantioxidantsZooxanthellaeCollagenNutraceuticalAntioxidantCassiopea andromedaQH301-705.5Biologyfatty acids03 medical and health sciencesNutraceuticalAntioxidant activitybiology.animalBotanyMediterranean SeaAnimalsZooxanthellate jellyfish14. Life underwaterAlien specieEcosystem030304 developmental biologyDietary Supplementbioactive marine compoundsAnimal010604 marine biology & hydrobiologybiology.organism_classificationFatty acidDietary SupplementsJellyfish
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Perthamides C-F, potent human antipsoriatic cyclopeptides

2011

Abstract Two new cyclopeptides, perthamides E and F were isolated from the polar extracts of the sponge Theonella swinhoei . The new structures, featuring an unprecedented β-amino acid unit (AHMOA), were determined by interpretation of NMR and MS data. The absolute configuration of the AHMOA residue was proposed on the basis of quantum chemical calculation of NMR chemical shifts. Perthamides were proved to inhibit TNF-α and IL-8 release in primary human keratinocytes cells and therefore could represent potentially leads for the treatment of psoriasis.

Quantum chemicalchemistry.chemical_classificationTheonella swinhoeiStereochemistryChemical shiftOrganic ChemistryAbsolute configurationTheonella swinhoeicyclopeptidesBiochemistryCombinatorial chemistryCyclic peptideResidue (chemistry)Anti-Inflammatory activitychemistryinflammationDrug DiscoveryMarine compoundsCyclic peptidesmarine natural product
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